Move inetpub folder on SharePoint

Is good practice on the production environment place inetpub directory on the different drive from system drive, for example on D:\. When you create a new SharePoint application you can specify which directory save  data but this require remember to change each time this directory. To avoid any inconvenience I suggest change the default parameter directely on regedit so when you create a new SharePoint Web Application, Central Admin will use by default this new directory. For this scope, open Regedit and locate this path HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\InetStp and change value of PathWWWRoot key with your new Path

Now when you create a new Web Application, SharePoint will use this new directory: